The significance of anti-streptokinase antibodies

Significance of anti - GBM antibodies

of proteinuria in patients with a long standing history of diabetes mellitus (DM). Primary glomerulonephritis, such as IgA nephropathy can superimpose on a background of diabetic glomerulosclerosis.1 In 1998, Tejinder et al,2 reported a case of anti glomerular basement membrane (GBM) nephritis superimposed on diabetic nephropathy in a 57 year old man. Then in 1999 Merlin et al3 reported simulta...

the effect of recombinant tissue plasminogen activator (r-tpa) on quantitation of neutralising anti-streptokinase antibodies

the measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen. neutralising titration test is a commonly used classical assay for measuring anti-streptokinase antibodies and in this assay the ability of anti-streptokinase antibodies in patients' sera in preventing the lytic ef...

The distribution of antibodies to streptokinase.

To determine the distribution of antibodies to streptokinase that might be anticipated in patients requiring treatment with streptokinase, specific anti-streptokinase antibody titres were determined in a group of subjects from the general population and in a group of patients presenting with acute myocardial infarction. Enzyme-linked immunosorbent assays were developed to measure specific anti-...

Are streptokinase antibodies clinically important?

The Effect of Recombinant Tissue Plasminogen Activator (r-tPA) on Quantitation of Neutralising Anti-Streptokinase Antibodies.

The measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen. Neutralising titration test is a commonly used classical assay for measuring anti-streptokinase antibodies and in this assay the ability of anti-streptokinase antibodies in patients' sera in preventing the lytic ef...